Read the following passage and choose the best answer (A, B, C, D):
Aspirin's origins go back at least as early as 1758. In that year, Englishman Edward Stone noticed a distinctive bitter flvor in the bark of the willow tree. To Stone, this particular bark seem to have much in common with "Peruvian Bark", which had been used medicinally since the 1640s to bring down fevers and to treat malaria, stone decided to test the effectiveness of the willow bark. He obtained some, pulverized it into tiny pieces, and conducted experiments on its properties. His tests demonstrated that this pulverized willow bark was effective both in reducing high temperatures and in relieving aches and pains. In 1763, stone presented his tiding to the British Royal Society. Several decades later, further studies on the medicinal value of the willow bark were being conducted by two Italian scientists. These chemists, Brugnatelli and Fontana, determined that the active chemical that was responsible for the medicinal characteristics in the willow bark was the chemical salicin, which is the active ingredient of today's aspirin. The name "aspirin" is the trade name of the drug based on the chemical salicin, properly known as acetylsalicylic acid.The trade name "aspirin" was invented for the drug in the 1890s by the Bayer Drug Company in Germany. The fist bottles of aspirin actually went on sale to the publicjust prior to the turn of the century, in 1899.
1. According to the passage, aspirin originated:
